Cannabis Extract May Improve Children with Autism Spectrum Disorder

A new study from the University of São Paulo in Brazil suggests that the cannabis extract cannabidiol (CBD) may help improve behavior and alleviate common symptoms in children and adolescents with autism spectrum disorder (ASD).

"The prevalence of autism spectrum disorder (ASD) diagnoses among children and adolescents is increasing globally, but many treatment approaches are ineffective," lead researcher Dr. Lara Branco told the New York Post.

Autism Spectrum Treatment

"ASD," which stands for "autism spectrum disorder," is a broad term encompassing a group of developmental conditions characterized by repetitive behaviors, communication difficulties, and difficulties with social interactions. The number of autism diagnoses in the United States has risen dramatically in recent years, increasing by a staggering 175% between 2011 and 2022, primarily due to a sharp rise in cases among young adults. Today, the Centers for Disease Control and Prevention (CDC) estimates that one in 36 American children has autism.

Studies show that emotional and behavioral problems are more common in young people with autism than in their neurotypical peers, significantly impacting the quality of life for the child and their family.

Professor Gert Daum, President of the European Psychiatric Association, said: "Autism spectrum disorder can be extremely frustrating for all involved: parents of children and adolescents with the disorder, and treating clinicians. Much of this frustration stems from finding an effective treatment option that alleviates symptoms."

Cannabis Extract

CBD, a natural compound from the cannabis plant, is a drug gaining increasing attention for its potential health benefits. Unlike THC—the psychoactive compound that causes a feeling of euphoria—CBD does not produce intoxicating effects, and across America, all 50 states have laws legalizing it with varying degrees of restrictions.

While previous studies have hinted at CBD's potential in managing symptoms of autism spectrum disorder, comprehensive research on its effectiveness and risks has been limited.

To fill this gap, researchers analyzed three clinical trials that investigated the use of cannabidiol (CBD) extracts in the treatment of 276 participants aged 5 to 21 with autism spectrum disorder, 78% of whom were male.

Key Study Findings

The team found that the CBD extract improved participants' social responsiveness, reduced disruptive behavior, alleviated anxiety, and improved sleep quality. Importantly, CBD did not cause more side effects compared to placebo, suggesting it has a "positive safety profile."

The study authors stated, "These findings support the feasibility of considering CBD extracts in autism spectrum disorder treatment plans."

The researchers emphasized the need for larger, more rigorous trials to fully evaluate the drug's safety and effectiveness.