First Baby Born from a Transplanted Uterus in a European Country

For the first time in the United Kingdom, a baby girl has been born after her mother received a uterus transplant from her older sister, a London hospital reported.

Amy Isabel was born on February 27, 2025, at Queen Charlotte and Chelsea Hospital, two years after her mother, Grace Davidson, 36, underwent a uterus transplant because she was born without one. Both are in good health.

"We were given the best gift we could have hoped for," said Davidson, expressing her hope that this technology will in the future "provide an additional option for women who would otherwise be unable to bear children."

Rare Condition

Grace Davidson suffers from a rare condition called Myelomeningocele Rokitansky syndrome, or MRKH, which causes the uterus to be underdeveloped or even absent.

This disease affects one in every five thousand women. The affected woman's ovaries are healthy and produce eggs, making it possible to implant an embryo obtained through in vitro fertilization after a uterus transplant.

Birth from a Uterus Transplant

The baby was named Amy Isabel after her aunt, Amy Purdy, and surgeon Isabel Quiroga, who performed the transplant for her mother with Professor Richard Smith. Amy Purdy, 42, now has two children.

Grace Davidson had to undergo immunosuppressive treatment to prevent her body from rejecting the transplanted uterus. The operation was performed in February at the Oxford Transplant Centre in southern England.

"I'm overjoyed," said gynecological surgeon Richard Smith, a lead on the British Living Donor Program. "After 25 years of research, we've finally had a baby."

More than 100 uterus transplants have been performed worldwide since the first in Sweden in 2013, resulting in the birth of around 50 healthy babies.